Junctional Cleft [Ca 2+ ] i Measurements Using Novel Cleft-Targeted Ca 2+ Sensors
نویسندگان
چکیده
منابع مشابه
Junctional cleft [Ca²⁺]i measurements using novel cleft-targeted Ca²⁺ sensors.
RATIONALE Intracellular Ca(2+) concentration ([Ca(2+)]i) is regulated and signals differently in various subcellular microdomains, which greatly enhances its second messenger versatility. In the heart, sarcoplasmic reticulum Ca(2+) release and signaling are controlled by local [Ca(2+)]i in the junctional cleft ([Ca(2+)]Cleft), the small space between sarcolemma and junctional sarcoplasmic retic...
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ژورنال
عنوان ژورنال: Circulation Research
سال: 2014
ISSN: 0009-7330,1524-4571
DOI: 10.1161/circresaha.115.303582